Saturday, February 15, 2014

Enzyme Nomenclature

Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)


Table 1: Recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology on the Nomenclature and Classification of Enzymes by the Reactions they Catalyse

Subclass
Name
Enzyme file type
Oxidoreductases


EC 1.1
Acting on the CH-OH group of donors
EC 1.2
Acting on the aldehyde or oxo group of donors
EC 1.3
Acting on the CH-CH group of donors
EC 1.4
Acting on the CH-NH2 group of donors
EC 1.5
Acting on the CH-NH group of donors
EC 1.6
Acting on NADH or NADPH
EC 1.7
Acting on other nitrogenous compounds as donors
EC 1.8
Acting on a sulfur group of donors
EC 1.9
Acting on a heme group of donors
EC 1.10
Acting on diphenols and related substances as donors
EC 1.11
Acting on a peroxide as acceptor
EC 1.12
Acting on hydrogen as donor
EC 1.13
Acting on single donors with incorporation of molecular oxygen (oxygenases)
EC 1.14
Acting on paired donors, with incorporation or reduction of molecular oxygen
EC 1.15
Acting on superoxide radicals as acceptor
EC 1.16
Oxidising metal ions
EC 1.17
Acting on CH or CH2 groups
EC 1.18
Acting on iron-sulfur proteins as donors
EC 1.19
Acting on reduced flavodoxin as donor
EC 1.20
Acting on phosphorus or arsenic in donors
EC 1.21
Acting on X-H and Y-H to form an X-Y bond
EC 1.22
Acting on halogen in donors
EC 1.23
Reducing C-O-C group as acceptor
EC 1.97
Other oxidoreductases
Transferases


EC 2.1
Transferring one-carbon groups
EC 2.2
Transferring aldehyde or ketonic groups
EC 2.3
Acyltransferases
EC 2.4
Glycosyltransferases
EC 2.5
Transferring alkyl or aryl groups, other than methyl groups
EC 2.6
Transferring nitrogenous groups
EC 2.7
Transferring phosphorus-containing groups
EC 2.8
Transferring sulfur-containing groups
EC 2.9
Transferring selenium-containing groups
EC 2.10
Transferring molybdenum- or tungsten-containing groups
Hydrolases


EC 3.1
Acting on ester bonds
EC 3.2
Glycosylases
EC 3.3
Acting on ether bonds
EC 3.4
Acting on peptide bonds (peptidases)
EC 3.5
Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.6
Acting on acid anhydrides
EC 3.7
Acting on carbon-carbon bonds
EC 3.8
Acting on halide bonds
EC 3.9
Acting on phosphorus-nitrogen bonds
EC 3.10
Acting on sulfur-nitrogen bonds
EC 3.11
Acting on carbon-phosphorus bonds
EC 3.12
Acting on sulfur-sulfur bonds
EC 3.13
Acting on carbon-sulfur bonds
Lyases


EC 4.1
Carbon-carbon lyases
EC 4.2
Carbon-oxygen lyases
EC 4.3
Carbon-nitrogen lyases
EC 4.4
Carbon-sulfur lyases
EC 4.5
Carbon-halide lyases
EC 4.6
Phosphorus-oxygen lyases
EC 4.7
Carbon-phosphorus lyases
EC 4.99
Other lyases
Isomerases


EC 5.1
Racemases and epimerases
EC 5.2
cis-trans-Isomerases
EC 5.3
Intramolecular isomerases
EC 5.4
Intramolecular transferases (mutases)
EC 5.5
Intramolecular lyases
EC 5.99
Other isomerases
Ligases


EC 6.1
Forming carbon—oxygen bonds
EC 6.2
Forming carbon—sulfur bonds
EC 6.3
Forming carbon—nitrogen bonds
EC 6.4
Forming carbon—carbon bonds
EC 6.5
Forming phosphoric ester bonds
EC 6.6
Forming nitrogen—metal bonds

Reference: http://www.chem.qmul.ac.uk/iubmb/enzyme/

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